Grip strength modifies the association between estimated glomerular filtration rate and all-cause mortality

Publication type

Journal Article

Published in

Nephrology Dialysis Transplantation


Per-Ola Sundin, Ruzan Udumyan, Katja Fall and Scott Montgomery

Publication date


Chronic kidney disease (CKD) with reduced glomerular filtration rate (GFR) represents a high-magnitude increased risk for cardiovascular disease (CVD) and all-cause mortality (ACM). The main non-GFR determinant of the endogenous filtration marker creatinine is its production rate in muscle. Stratification of GFR by a marker of muscle function (grip strength) associated with muscle mass may remove heterogeneity, providing a more accurate marker of mortality risk.
This study evaluates whether grip strength identifies ACM risk associated with estimated GFR (eGFR) from serum creatinine in a subsample of the UK Household Longitudinal Survey (UKHLS).

Volume and page numbers

34, 1799-1801





Medicine, Health and Biology


Open Access; © The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA.; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.