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Search found 32 items

The association between self-rated health and underlying biomarker levels is modified by age, gender, and household income: evidence from Understanding Society – the UK Household Longitudinal Study

M. Pia Chaparro, Amanda Hughes, Meena Kumari, Michaela Benzeval

Social GroupsDemographyIncome DynamicsHealthBiology


Are flexible work arrangements associated with lower levels of chronic stress-related biomarkers? A study of 6025 employees in the UK Household Longitudinal Study

Tarani Chandola, Cara L. Booker, Meena Kumari, Michaela Benzeval

Sociology Of LabourLabour MarketWell BeingHealthCaregivingBiology


Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

Georgina Mansell, Tyler J. Gorrie-Stone, Yanchun Bao, Meena Kumari, Leonard S. Schalkwyk

Statistical AnalysisBiologyGenetics


Assessing the robustness of sisVIVE in a Mendelian randomization study to estimate the causal effect of body mass index on income using multiple SNPs from Understanding Society

Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari

Income DynamicsBiologyGenetics


Early-life inequalities and biological ageing: a multisystem Biological Health Score approach in Understanding Society

Maryam Karimi, Raphaële Castagné, Cyrille Delpierre, Gaëlle Albertus, Eloïse Berger

HealthLife Course AnalysisSocial StratificationBiology


Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals

Victoria Garfield, Ghazaleh Fatemifar, Caroline Dale, Melissa Smart, Yanchun Bao

Science And TechnologyHealthBiologyGenetics


The authors reply

Amanda Hughes, Yanchun Bao, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon

HealthLife Course AnalysisSocial StratificationBiologyGenetics


The transferability of lipid-associated loci across African, Asian and European cohorts

Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Deepti Gurdasani

MedicineDemographyEthnic GroupsHealthBiologyGenetics


Testosterone, risk, and socioeconomic position in British men: exploring causal directionality

Amanda Hughes, Meena Kumari

Social StratificationBiologyGenetics


Multivariate genome-wide analyses of the well-being spectrum

Bart M. L. Baselmans, Rick Jansen, Hill F. Ip, Jenny van Dongen, Abdel Abdellaoui

PsychologyMedicineScience And TechnologyWell BeingHealthBiologyGenetics


Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Richard Karlsson Linnér, Pietro Biroli, Edward Kong, S. Fleur W. Meddens, Robbee Wedow

Drug/Alcohol AbuseSocial BehaviourBiologyGenetics


Socioeconomic position and DNA methylation age acceleration across the lifecourse

Amanda Hughes, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill

HealthLife Course AnalysisSocial StratificationBiologyGenetics


Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian

EducationBiologyGenetics


A comparison of robust methods for Mendelian randomization using multiple genetic variants

Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari

Income DynamicsBiologyGenetics


Age modification of the relationship between C-reactive protein and fatigue: findings from Understanding Society (UKHLS)

Amanda Hughes, Meena Kumari

MedicineHealthBiology


Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove

MedicineScience And TechnologyResearchSurveysBiologyGenetics


Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


Gene-environment interactions between education and body mass: evidence from the UK and Finland

Vikesh Amin, Petri Böckerman, Jutta Viinikainen, Melissa Smart, Yanchun Bao

EducationHealthBiologyGenetics


Associations of C-reactive protein and psychological distress are modified by antidepressants, supporting an inflammatory depression subtype: findings from UKHLS

Amanda Hughes, Meena Kumari

PsychologyMedicineWell BeingHealthBiology


Vitamin D and cognitive function: a Mendelian randomisation study

Jane Maddock, Ang Zhou, Alana Cavadino, Elżbieta Kuźma, Yanchun Bao

Older PeoplePsychologyScience And TechnologyHealthLife Course AnalysisGenetics


Unemployment and inflammatory markers in England, Wales and Scotland, 1998–2012: meta-analysis of results from 12 studies

Amanda Hughes, Meena Kumari, Anne McMunn, Mel Bartley

MedicineUnemploymentWell BeingHealthBiology


A guide to the biomarker data in the CLOSER studies. A catalogue across cohort and longitudinal studies

Milagros Ruiz, Michaela Benzeval, Meena Kumari

Science And TechnologyHealthSurveysBiology


Biomarker, genetics and epigenetics data

Meena Kumari, Melissa Smart, Michaela Benzeval

Science And TechnologySurveysBiologyGenetics


Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: findings from Understanding Society

Apostolos Davillas, Michaela Benzeval, Meena Kumari

Science And TechnologyHealthLife Course AnalysisSocial StratificationBiology