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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter

HealthBiologyGenetics


Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals

Victoria Garfield, Ghazaleh Fatemifar, Caroline Dale, Melissa Smart, Yanchun Bao, Clare H. Llewellyn, Andrew Steptoe, Delilah Zabaneh, Meena Kumari

Science And TechnologyHealthBiologyGenetics


The authors reply

Amanda Hughes, Yanchun Bao, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill, Joe Burrage, Leo Schalkwyk, Meena Kumari

HealthLife Course AnalysisSocial StratificationBiologyGenetics


Multivariate genome-wide analyses of the well-being spectrum

Bart M. L. Baselmans, Rick Jansen, Hill F. Ip, Jenny van Dongen, Abdel Abdellaoui, Margot P. van de Weijer, Yanchun Bao, Melissa Smart, Meena Kumari, Gonneke Willemsen

PsychologyMedicineScience And TechnologyWell BeingHealthBiologyGenetics


Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Richard Karlsson Linnér, Pietro Biroli, Edward Kong, S. Fleur W. Meddens, Robbee Wedow, Mark Alan Fontana, Maël Lebreton, Stephen P. Tino, Abdel Abdellaoui, Anke R. Hammerschlag

Drug/Alcohol AbuseHealthSocial BehaviourBiologyGenetics