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Search found 23 items

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

David M. Brazel, Yu Jiang, Jordan M. Hughey, Valérie Turcot, Xiaowei Zhan

Drug/Alcohol AbuseMedicineScience And TechnologyPsychiatryHealthBiologyGenetics


Socioeconomic position and DNA methylation age acceleration across the lifecourse

Amanda Hughes, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill

HealthLife Course AnalysisSocial StratificationBiologyGenetics


Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon

MedicineChild DevelopmentHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki

MedicineScience And TechnologyHealthBiologyGenetics


A single complex Agpat2 allele in a patient with partial lipodystrophy

Marjoleine F. Broekema, Maarten P.G. Massink, Joep De Ligt, Edwin C.A. Stigter, Houshang Monajemi

MedicineHealthBiologyGenetics


Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian

EducationBiologyGenetics


Caring for carers: the lives of family carers in the UK

Kathryn Petrie, James Kirkup

DisabilityTime UseLabour MarketHouseholdsOrganizations And FirmsPublic PolicyWell BeingHealthSocial PolicyCaregiving


A comparison of robust methods for Mendelian randomization using multiple genetic variants

Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari

Income DynamicsBiologyGenetics


Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove

MedicineScience And TechnologyHealthGenetics


Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

Konstantinos Hatzikotoulas, Andreas Roposch, Karan M. Shah, Matthew J. Clark, Selina Bratherton

MedicineHealthBiologyGenetics


Policy impact: building a more productive society – could the industrial strategy make a difference?

Raj Patel

Organizations And FirmsEconomicsPublic PolicySocieties


Self-employment and workplace wellbeing -PhD thesis-

Jingjing Qu

Labour MarketOrganizations And FirmsWell Being


Insights from a new division of the self-employed: analysis of characteristics, earnings returns and labour market transitions using the BHPS and UKHLS -PhD thesis-

Hiba Hussein

Labour MarketOrganizations And FirmsEconomicsWages And Earnings


Self-exploitation or successful entrepreneurship? The effects of personal capital on variable outcomes from self-employment

Andrew Atherton, Dongxu Wu, Zhongmin Wu

Human CapitalManagement: BusinessLabour MarketOrganizations And FirmsIncome Dynamics


Self-employment and allostatic load

Pankaj C. Patel, Marcus T. Wolfe, Trenton A. Williams

Management: BusinessLabour MarketOrganizations And FirmsWell BeingHealthBiology


Universal Credit: supporting self-employment. Eleventh report of session 2017–19. Report, together with formal minutes relating to the report. Ordered by the House of Commons to be printed 2 May 2018

Management: BusinessOrganizations And FirmsPublic PolicyWelfare BenefitsGovernment


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon

MedicineChild DevelopmentHealthBiologyGenetics


Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove

MedicineScience And TechnologyResearchSurveysBiologyGenetics


Testosterone and tendency to engage in self-employment

Nicos Nicolaou, Pankaj C. Patel, Marcus T. Wolfe

Management: BusinessLabour MarketOrganizations And FirmsSocial BehaviourBiology


Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


A novel variant in GLIS3 is associated with osteoarthritis

Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger

MedicineScience And TechnologyHealthGenetics


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice

MedicineScience And TechnologyHealthBiologyGenetics