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Search found 27 items

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

David M. Brazel, Yu Jiang, Jordan M. Hughey, Valérie Turcot, Xiaowei Zhan

Drug/Alcohol AbuseMedicineScience And TechnologyPsychiatryHealthBiologyGenetics


Socioeconomic position and DNA methylation age acceleration across the lifecourse

Amanda Hughes, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill

HealthLife Course AnalysisSocial StratificationBiologyGenetics


Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon

MedicineChild DevelopmentHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki

MedicineScience And TechnologyHealthBiologyGenetics


A single complex Agpat2 allele in a patient with partial lipodystrophy

Marjoleine F. Broekema, Maarten P.G. Massink, Joep De Ligt, Edwin C.A. Stigter, Houshang Monajemi

MedicineHealthBiologyGenetics


2018 IF index: how does the wellbeing of today's twentysomethings compare to previous cohorts?

David Kingman

Social ChangeYoung PeopleWell BeingLife Course Analysis


Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian

EducationBiologyGenetics


A comparison of robust methods for Mendelian randomization using multiple genetic variants

Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari

Income DynamicsBiologyGenetics


Poverty and social exclusion in the UK. Volume 2 - the dimensions of disadvantage

Social ExclusionDemographySocial ChangePovertyLiving Standards


Young people in the labour market: past, present, future

Andy Furlong, John Goodwin, Henrietta O'Connor, Sarah Hadfield, Stuart Hall

Sociology Of LabourSocial ChangeYoung PeopleLabour MarketEconomics


Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove

MedicineScience And TechnologyHealthGenetics


Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

Konstantinos Hatzikotoulas, Andreas Roposch, Karan M. Shah, Matthew J. Clark, Selina Bratherton

MedicineHealthBiologyGenetics


Insights 2018-19: findings from the UK Household Longitudinal Study

Environmental SociologyOlder PeopleSocial ChangeHouseholdsPublic PolicyLife Course AnalysisSurveysSociology Of Households


Foreword

David Walker

Social ChangeHouseholdsPublic PolicyResearchLife Course AnalysisSurveys


Differences in partnership and marital status at first birth by women’s and their partners’ education: evidence from Britain 1991–2012

Nitzan Peri-Rotem, Jacqueline Scott

DemographySocial ChangeEducationLabour MarketFamily Formation And DissolutionChildbearing: Fertility


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon

MedicineChild DevelopmentHealthBiologyGenetics


Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove

MedicineScience And TechnologyResearchSurveysBiologyGenetics


Measuring National Well-being: quality of life in the UK, 2018

Rhian Jones, Chris Randall

PsychologyDemographySocial ChangeLiving StandardsWell BeingSocieties


The ties that bind: citizenship and civic engagement in the 21st Century: Select Committee on Citizenship and Civic Engagement, report of Session 2017–19

CitizenshipSocial ChangePublic PolicyGovernmentSocieties


Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


A novel variant in GLIS3 is associated with osteoarthritis

Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger

MedicineScience And TechnologyHealthGenetics


Children’s well-being and social relationships, UK: 2018

Edward Pyle, Charlotte Hassell

PsychologySocial ChangeYoung PeopleChild DevelopmentWell BeingSocial PolicySociology Of Households


One in four: a profile of single parents in the UK

Sumi Rabindrakumar

Lone ParentsSocial ChangeLabour MarketHouseholdsIncome DynamicsFinance


Young people’s travel – what’s changed and why? Review and analysis. Report to Department for Transport. Executive summary

Kiron Chatterjee, Phil Goodwin, Ben Clark, Juliet Jain, Steve Melia

Social ChangeYoung PeopleEconomicsLife Course AnalysisTransportTravel