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Search found 33 items

Systematic underestimation of the epigenetic clock and age acceleration in older subjects

Louis Y. El Khoury, Tyler Gorrie-Stone, Melissa Smart, Amanda Hughes, Yanchun Bao, Alexandria Andrayas, Joe Burrage, Eilis Hannon, Meena Kumari, Jonathan Mill

Older PeopleLife Course AnalysisBiologyGenetics


Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig

HealthBiologyGenetics


P06 Genetics of juvenile idiopathic arthritis: the identification of a novel risk locus and clinical subgroup analysis -conference paper abstract-

John Bowes, Annie Yarwood, Samantha Smith, Damian Tarasek, Wendy Thomson

MedicineHealthBiologyGenetics


Associations of autozygosity with a broad range of human phenotypes

David W. Clark, Yukinori Okada, Kristjan H.S. Moore, Dan Mason, Nicola Pirastu, Ilaria Gandin, Hannele Mattsson, Catriona L.K. Barnes, Kuang Lin, Jing Hua Zhao

Childbearing: FertilityBiologyGenetics


The transferability of lipid loci across African, Asian and European cohorts

Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis

MedicineDemographyEthnic GroupsHealthBiologyGenetics


The UK citizenship process: political integration or marginalization?

David Bartram

PoliticsSocial ExclusionSocial InclusionMigrationPublic PolicyEthnic GroupsSocietiesSocial CapitalSociology


Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics


Migration versus immobility, and ties to parents

John Ermisch, Clara H. Mulder

Area EffectsGeographyDemographyMigrationHouseholdsSociologyHousing Market


Immigrants’ relative income and life satisfaction: comparison groups from a multi-generational perspective

Jing Shen, Irena Kogan

MigrationIncome DynamicsEthnic GroupsWell BeingSociologySocial Psychology


Understanding cultural omnivores: social and political attitudes

Tak Wing Chan

PsychologyEducationArtsSocial AttitudesSociologySocial Mobility


Does the religious context matter? The causal effect of religious diversity on individual life satisfaction in the UK

Jing Shen, Irena Kogan

Social GroupsArea EffectsGeographyReligionEthnic GroupsWell BeingSocial PsychologyRace Relations


Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Ayush Giri, Jacklyn N. Hellwege, Jacob M. Keaton, Jihwan Park, Chengxiang Qiu, Helen R. Warren, Eric S. Torstenson, Csaba P. Kovesdy, Yan V. Sun, Otis D. Wilson

Ethnic GroupsHealthBiologyGenetics


'The Eastern Europeans are taking all the Asian jobs': ethnic minority support for Brexit

Neema Begum

PoliticsSocial GroupsPublic OpinionPsychologyElections. Electoral BehaviourDemographyLabour MarketEconomicsEthnic GroupsSocial AttitudesRace Relations


Sex, lies and politics: the secret influences that drive our political choices

PoliticsPublic OpinionPsychologyElections. Electoral BehaviourSocial AttitudesSociologySocial Behaviour


Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

Georgina Mansell, Tyler J. Gorrie-Stone, Yanchun Bao, Meena Kumari, Leonard S. Schalkwyk, Jonathan Mill, Eilis Hannon

Statistical AnalysisBiologyGenetics


Assessing the robustness of sisVIVE in a Mendelian randomization study to estimate the causal effect of body mass index on income using multiple SNPs from Understanding Society

Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari

Income DynamicsBiologyGenetics


Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals

Victoria Garfield, Ghazaleh Fatemifar, Caroline Dale, Melissa Smart, Yanchun Bao, Clare H. Llewellyn, Andrew Steptoe, Delilah Zabaneh, Meena Kumari

Science And TechnologyHealthBiologyGenetics


Bigmelon: tools for analysing large DNA methylation datasets

Tyler J. Gorrie-Stone, Melissa Smart, Ayden Saffari, Karim Malki, Eilis Hannon, Joe Burrage, Jonathan Mill, Meena Kumari, Leonard C. Schalkwyk

Statistical AnalysisComputingGenetics


Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Phuwanat Sakornsakolpat, Dmitry Prokopenko, Maxime Lamontagne, Nicola F. Reeve, Anna L. Guyatt, Victoria E. Jackson, Nick Shrine, Dandi Qiao, Traci M. Bartz, Deog Kyeom Kim

Drug/Alcohol AbuseHealthBiologyGenetics


The evolutionary dynamics and fitness landscape of clonal haematopoiesis

Caroline J. Watson, Alana Papula, Yeuk P.G. Poon, Wing H. Wong, Andrew L. Young, Todd E. Druley, Daniel S. Fisher, Jamie R. Blundell

Older PeopleHealthLife Course AnalysisBiologyGenetics


New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Nick Shrine, Anna L. Guyatt, A. Mesut Erzurumluoglu, Victoria E. Jackson, Brian D. Hobbs, Carl A. Melbourne, Chiara Batini, Katherine A. Fawcett, Kijoung Song, Phuwanat Sakornsakolpat

HealthBiologyGenetics


Sexual orientation identity in relation to unhealthy body mass index: individual participant data meta-analysis of 93 429 individuals from 12 UK health surveys

J. Semlyen, T.J. Curtis, J. Varney

HealthSurveysSociology


Information, expectations and transition to higher education: final report

Adeline Delavande, Laura Fumagalli

Information NetworksYoung PeopleSocial StratificationHigher Education


The role of gender role attitudes and immigrant generation in ethnic minority women’s labor force participation in Britain

Senhu Wang

MigrationLabour MarketEthnic GroupsSocial AttitudesSociology


The authors reply

Amanda Hughes, Yanchun Bao, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill, Joe Burrage, Leo Schalkwyk, Meena Kumari

HealthLife Course AnalysisSocial StratificationBiologyGenetics