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Search found 17 items

The transferability of lipid loci across African, Asian and European cohorts

Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis

MedicineDemographyEthnic GroupsHealthBiologyGenetics


Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics


The transferability of lipid-associated loci across African, Asian and European cohorts

Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley

MedicineDemographyEthnic GroupsHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, Ibrahim Karaman

MedicineScience And TechnologyHealthBiologyGenetics


Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove, Traci M. Bartz, Ma'en Obeidat, Michael A. Province, Wei Gao, Beenish Qaiser

MedicineScience And TechnologyHealthGenetics


Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

Konstantinos Hatzikotoulas, Andreas Roposch, Karan M. Shah, Matthew J. Clark, Selina Bratherton, Vasanti Limbani, Julia Steinberg, Eleni Zengini, Kaltuun Warsame, Madhushika Ratnayake

MedicineHealthBiologyGenetics


A novel variant in GLIS3 is associated with osteoarthritis

Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger, Dániel Süveges, Julia Steinberg, Nigel William Rayner, Jeremy Mark Wilkinson, Kalliope Panoutsopoulou

MedicineScience And TechnologyHealthGenetics


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics


New blood pressure–associated loci identified in meta-analyses of 475 000 individuals

Aldi T. Kraja, James P. Cook, Helen R. Warren, Praveen Surendran, Chunyu Liu, Evangelos Evangelou, Alisa K. Manning, Niels Grarup, Fotios Drenos, Xueling Sim

MedicineScience And TechnologyHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, Ibrahim Karaman

MedicineScience And TechnologyHealthBiologyGenetics


A Genome-Wide Association Study of Dupuytren disease reveals 17 additional variants implicated in fibrosis

Michael Ng, Dipti Thakkar, Lorraine Southam, Paul Werker, Roel Ophoff, Kerstin Becker, Michael Nothnagel, Andre Franke, Peter Nürnberg, Ana Isabel Espirito-Santo

MedicineHealthBiologyGenetics


Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits

Lorraine Southam, Arthur Gilly, Dániel Süveges, Aliki-Eleni Farmaki, Jeremy Schwartzentruber, Ioanna Tachmazidou, Angela Matchan, Nigel W. Rayner, Emmanouil Tsafantakis, Maria Karaleftheri

MedicineScience And TechnologyHealthBiologyGenetics


Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Helen R. Warren, Evangelos Evangelou, Claudia P. Cabrera, He Gao, Meixia Ren, Borbala Mifsud, Ioanna Ntalla, Praveen Surendran, Chunyu Liu, James P. Cook

MedicineScience And TechnologyHealthBiologyGenetics


Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Praveen Surendran, Fotios Drenos, Robin Young, Helen Warren, James P. Cook, Alisa K. Manning, Niels Grarup, Xueling Sim, Daniel R. Barnes, Kate Witkowska

MedicineScience And TechnologyHealthBiologyGenetics


Meta-analysis of summary statistics from quantitative trait association studies with unknown sample overlap -conference paper abstract-

Arthur Gilly, Ioanna Tachmazidou, Eleftheria Zeggini

MedicineResearchBiologyGenetics


Height-reducing variants and selection for short stature in Sardinia

Magdalena Zoledziewska, Carlo Sidore, Charleston W. K. Chiang, Serena Sanna, Antonella Mulas, Maristella Steri, Fabio Busonero, Joseph H. Marcus, Andrea Maschio, Diego Ortega Del Vecchyo

MedicineScience And TechnologyHealthBiologyGenetics


Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

Thomas McKerrell, Naomi Park, Thaidy Moreno, Carolyn Grove, Hannes Ponstingl, Jonathan Stephens, Charles Crawley, Jenny Craig, Mike A. Scott, Clare Hodkinson

Older PeopleMedicineHealthBiologyGenetics