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Search found 13 items

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

David M. Brazel, Yu Jiang, Jordan M. Hughey, Valérie Turcot, Xiaowei Zhan, Jian Gong, Chiara Batini, J. Dylan Weissenkampen, MengZhen Liu, Daniel R. Barnes

Drug/Alcohol AbuseMedicineScience And TechnologyPsychiatryHealthBiologyGenetics


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon, Martin Kelemen, Kerrie McAloney, Jeremy McRae, Elizabeth J. Radford, Sui Yu

MedicineChild DevelopmentHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, Ibrahim Karaman

MedicineScience And TechnologyHealthBiologyGenetics


A single complex Agpat2 allele in a patient with partial lipodystrophy

Marjoleine F. Broekema, Maarten P.G. Massink, Joep De Ligt, Edwin C.A. Stigter, Houshang Monajemi, Jeroen De Ridder, Boudewijn M.T. Burgering, Gijs W. van Haaften, Eric Kalkhoven

MedicineHealthBiologyGenetics


Age modification of the relationship between C-reactive protein and fatigue: findings from Understanding Society (UKHLS)

Amanda Hughes, Meena Kumari

MedicineHealthBiology


Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove, Traci M. Bartz, Ma'en Obeidat, Michael A. Province, Wei Gao, Beenish Qaiser

MedicineScience And TechnologyHealthGenetics


Social patterning in grip strength and in its association with age; a cross sectional analysis using the UK Household Longitudinal Study (UKHLS)

Caroline Carney, Michaela Benzeval

MedicineHealthLife Course AnalysisSocial StratificationBiology


Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

Konstantinos Hatzikotoulas, Andreas Roposch, Karan M. Shah, Matthew J. Clark, Selina Bratherton, Vasanti Limbani, Julia Steinberg, Eleni Zengini, Kaltuun Warsame, Madhushika Ratnayake

MedicineHealthBiologyGenetics


Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari E. K. Niemi, Hilary C. Martin, Daniel L. Rice, Giuseppe Gallone, Scott Gordon, Martin Kelemen, Kerrie McAloney, Jeremy McRae, Elizabeth J. Radford, Sui Yu

MedicineChild DevelopmentHealthBiologyGenetics


Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove, Alissa Goodman, Rebecca L. Griggs, Alison Hall, Nina Hallowell, Meena Kumari

MedicineScience And TechnologyResearchSurveysBiologyGenetics


The effects of immigration on NHS waiting times

Osea Giuntella, Catia Nicodemo, Carlos Vargas Silva

Area EffectsGeographyMedicineDemographyMigrationEconomicsHealth


A novel variant in GLIS3 is associated with osteoarthritis

Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger, Dániel Süveges, Julia Steinberg, Nigel William Rayner, Jeremy Mark Wilkinson, Kalliope Panoutsopoulou

MedicineScience And TechnologyHealthGenetics


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics