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Search found 11 items

The transferability of lipid loci across African, Asian and European cohorts

Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis

MedicineDemographyEthnic GroupsHealthBiologyGenetics


Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics


GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

Unnur Styrkarsdottir, Olafur A. Stefansson, Kristbjorg Gunnarsdottir, Gudmar Thorleifsson, Sigrun H. Lund, Lilja Stefansdottir, Kristinn Juliusson, Arna B. Agustsdottir, Florian Zink, Gisli H. Halldorsson


Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data

Ioanna Tachmazidou, Konstantinos Hatzikotoulas, Lorraine Southam, Jorge Esparza-Gordillo, Valeriia Haberland, Jie Zheng, Toby Johnson, Mine Koprulu, Eleni Zengini, Julia Steinberg

HealthGenetics


The transferability of lipid-associated loci across African, Asian and European cohorts

Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley

MedicineDemographyEthnic GroupsHealthBiologyGenetics


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice, Rebecca S. Fine, Jonathan P. Bradfield, Tõnu Esko, Ayush Giri, Mariaelisa Graff

MedicineScience And TechnologyHealthBiologyGenetics


New blood pressure–associated loci identified in meta-analyses of 475 000 individuals

Aldi T. Kraja, James P. Cook, Helen R. Warren, Praveen Surendran, Chunyu Liu, Evangelos Evangelou, Alisa K. Manning, Niels Grarup, Fotios Drenos, Xueling Sim

MedicineScience And TechnologyHealthBiologyGenetics


A Genome-Wide Association Study of Dupuytren disease reveals 17 additional variants implicated in fibrosis

Michael Ng, Dipti Thakkar, Lorraine Southam, Paul Werker, Roel Ophoff, Kerstin Becker, Michael Nothnagel, Andre Franke, Peter Nürnberg, Ana Isabel Espirito-Santo

MedicineHealthBiologyGenetics


Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits

Ioanna Tachmazidou, Dániel Süveges, Josine L. Min, Graham R. S. Ritchie, Julia Steinberg, Klaudia Walter, Valentina Iotchkova, Jeremy Schwartzentruber, Jie Huang, Yasin Memari

Science And TechnologyHealthBiologyGenetics


Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits

Lorraine Southam, Arthur Gilly, Dániel Süveges, Aliki-Eleni Farmaki, Jeremy Schwartzentruber, Ioanna Tachmazidou, Angela Matchan, Nigel W. Rayner, Emmanouil Tsafantakis, Maria Karaleftheri

MedicineScience And TechnologyHealthBiologyGenetics


Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Praveen Surendran, Fotios Drenos, Robin Young, Helen Warren, James P. Cook, Alisa K. Manning, Niels Grarup, Xueling Sim, Daniel R. Barnes, Kate Witkowska

MedicineScience And TechnologyHealthBiologyGenetics