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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Ghazaleh Fatemifar
Associations of autozygosity with a broad range of human phenotypes
David W. Clark, Yukinori Okada, Kristjan H.S. Moore, Dan Mason, Nicola Pirastu
The transferability of lipid loci across African, Asian and European cohorts
Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin
The association between self-rated health and underlying biomarker levels is modified by age, gender, and household income: evidence from Understanding Society – the UK Household Longitudinal Study
M. Pia Chaparro, Amanda Hughes, Meena Kumari, Michaela Benzeval
Are flexible work arrangements associated with lower levels of chronic stress-related biomarkers? A study of 6025 employees in the UK Household Longitudinal Study
Tarani Chandola, Cara L. Booker, Meena Kumari, Michaela Benzeval
Early-life inequalities and biological ageing: a multisystem Biological Health Score approach in Understanding Society
Maryam Karimi, Raphaële Castagné, Cyrille Delpierre, Gaëlle Albertus, Eloïse Berger
Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array
Georgina Mansell, Tyler J. Gorrie-Stone, Yanchun Bao, Meena Kumari, Leonard S. Schalkwyk
Assessing the robustness of sisVIVE in a Mendelian randomization study to estimate the causal effect of body mass index on income using multiple SNPs from Understanding Society
Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari
Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals
Victoria Garfield, Ghazaleh Fatemifar, Caroline Dale, Melissa Smart, Yanchun Bao
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Amanda Hughes, Yanchun Bao, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon
The transferability of lipid-associated loci across African, Asian and European cohorts
Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Deepti Gurdasani
Testosterone, risk, and socioeconomic position in British men: exploring causal directionality
Multivariate genome-wide analyses of the well-being spectrum
Bart M. L. Baselmans, Rick Jansen, Hill F. Ip, Jenny van Dongen, Abdel Abdellaoui
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Richard Karlsson Linnér, Pietro Biroli, Edward Kong, S. Fleur W. Meddens, Robbee Wedow
Socioeconomic position and DNA methylation age acceleration across the lifecourse
Amanda Hughes, Melissa Smart, Tyler Gorrie-Stone, Eilis Hannon, Jonathan Mill
Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits
Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian
A comparison of robust methods for Mendelian randomization using multiple genetic variants
Yanchun Bao, Paul Clarke, Melissa Smart, Meena Kumari
Age modification of the relationship between C-reactive protein and fatigue: findings from Understanding Society (UKHLS)
Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure
Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove
Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits
Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes
Gene-environment interactions between education and body mass: evidence from the UK and Finland
Vikesh Amin, Petri Böckerman, Jutta Viinikainen, Melissa Smart, Yanchun Bao
Associations of C-reactive protein and psychological distress are modified by antidepressants, supporting an inflammatory depression subtype: findings from UKHLS
Unemployment and inflammatory markers in England, Wales and Scotland, 1998–2012: meta-analysis of results from 12 studies
Amanda Hughes, Meena Kumari, Anne McMunn, Mel Bartley
A guide to the biomarker data in the CLOSER studies. A catalogue across cohort and longitudinal studies
Milagros Ruiz, Michaela Benzeval, Meena Kumari