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Search found 49 items

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

David M. Brazel, Yu Jiang, Jordan M. Hughey, Valérie Turcot, Xiaowei Zhan

Drug/Alcohol AbuseMedicineScience And TechnologyPsychiatryHealthBiologyGenetics


Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals

Victoria Garfield, Ghazaleh Fatemifar, Caroline Dale, Melissa Smart, Yanchun Bao

Science And TechnologyHealthBiologyGenetics


Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki

MedicineScience And TechnologyHealthBiologyGenetics


Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove

MedicineScience And TechnologyHealthGenetics


Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure

Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove

MedicineScience And TechnologyResearchSurveysBiologyGenetics


Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

Eilis Hannon, Tyler J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes

Science And TechnologyResearchHealthBiologyGenetics


A novel variant in GLIS3 is associated with osteoarthritis

Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger

MedicineScience And TechnologyHealthGenetics


The use of new technologies to measure socio-economic and environmental concepts in longitudinal studies

Annette Jäckle, Alessandra Gaia, Michaela Benzeval

Information And Communication TechnologiesScience And TechnologySurvey MethodologySurveys


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, Claudia Schurmann, Anne E. Justice

MedicineScience And TechnologyHealthBiologyGenetics


New blood pressure–associated loci identified in meta-analyses of 475 000 individuals

Aldi T. Kraja, James P. Cook, Helen R. Warren, Praveen Surendran, Chunyu Liu

MedicineScience And TechnologyHealthBiologyGenetics


Vitamin D and cognitive function: a Mendelian randomisation study

Jane Maddock, Ang Zhou, Alana Cavadino, Elżbieta Kuźma, Yanchun Bao

Older PeoplePsychologyScience And TechnologyHealthLife Course AnalysisGenetics


Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki

MedicineScience And TechnologyHealthBiologyGenetics


Novel blood pressure locus and gene discovery using Genome-Wide Association Study and expression data sets from blood and the kidney

Louise Wain, Ahmad Vaez, Rick Jansen, Roby Joehanes, Peter J. van der Most

Science And TechnologyHealthBiologyGenetics


Mixing modes and measurement methods in longitudinal studies

Annette Jäckle, Alessandra Gaia, Michaela Benzeval

Information And Communication TechnologiesScience And TechnologyEconomicsSurvey MethodologySurveys


A guide to the biomarker data in the CLOSER studies. A catalogue across cohort and longitudinal studies

Milagros Ruiz, Michaela Benzeval, Meena Kumari

Science And TechnologyHealthSurveysBiology


Does clean air make you happy?

Sarah Knight

Environmental SociologyArea EffectsGeographyScience And TechnologyWell BeingHealth


Smoking history and genome wide DNA methylation in Understanding Society (wave 3)

Alex Andrayas

Drug/Alcohol AbuseScience And TechnologyHealthSocial StratificationBiologyGenetics


Integrating genetic and epigenetic variation in the Understanding Society: mQTLs and complex trait polygenic scores

Eilis Hannon

Science And TechnologyHealthBiologyGenetics


Genome wide methylation analysis of lipids in Understanding Society (wave 3)

Tyler Gorrie-Stone

Science And TechnologyHealthBiologyGenetics


Epigenetic profiles, ageing and social position

Amanda Hughes

Older PeopleScience And TechnologyHealthLife Course AnalysisSocial StratificationBiologyGenetics


Biomarker, genetics and epigenetics data

Meena Kumari, Melissa Smart, Michaela Benzeval

Science And TechnologySurveysBiologyGenetics


Evidence for large-scale gene-by-smoking interaction effects on pulmonary function

H. Aschard, Martin D. Tobin, D. B. Hancock, D. Skurnik, A. Sood

Drug/Alcohol AbuseMedicineScience And TechnologyHealthBiologyGenetics


Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity

Audrey E. Hendricks, Elena G. Bochukova, Gaëlle Marenne, Julia M. Keogh, Neli Atanassova

Science And TechnologyYoung PeopleHealthBiologyGenetics


Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits

Ioanna Tachmazidou, Dániel Süveges, Josine L. Min, Graham R. S. Ritchie, Julia Steinberg

Science And TechnologyHealthBiologyGenetics


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